Detection of myocardial ischemia by CT perfusion imaging in comparison with N-13 ammonia PET

Detection of myocardial ischemia by CT perfusion imaging in comparison with N-13 ammonia PET - Myocardial CT perfusion versus N-13 ammonia PET

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015856

Enrollment

Registered

2014-12-05

Start date

2014-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

Cardiac CT and N-13 ammonia PET for patients with coronary artery disease

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects with written informed consent

Exclusion criteria

Exclusion criteria: 1. Body weight >75kg 2. Elevated serum creatinine (>1.5 mg/dL) or calculated creatinine clearance of <60 mL/min 3. History of allergic reaction to iodinated contrast media, History of contrast-induced nephropathy 4. Atrial fibrillation or uncontrolled tachyarrhythmia 5. Advanced atrioventricular block (second- or third-degree heart block) 6. Evidence of acute coronary syndrome 7. Known or suspected moderate or severe aortic stenosis 8. Evidence of severe symptomatic heart failure (New York Heart Association class III or IV) 9. Previous coronary artery bypass or other cardiac surgery 10. Coronary artery intervention within the past 6 months 11. Contraindications to vasodilatory stress (systolic blood pressure <90, recent use of dipyridamole- and dipyridamole-containing medications, recent use of methylxanthines, such as aminophylline and caffeine) 12. Profound sinus bradycardia (fewer than 40 beats per minute) 13. Known or suspected intolerance or contraindication to beta-blockers (including known allergy to betablockers, history of moderate to severe bronchospastic lung disease, including moderate to severe asthma, severe pulmonary disease with the use of inhaled bronchodilator over the past year) 14. Presence of intracardiac devices, such as intracardiac defibrillator or metallic implants within the imaging field of view 15. History of high radiation exposure (>2 nuclear or multidetector CT studies) in the 1 month before consent 16. The presence of any other history or condition that the investigator judged to be a significant reason for exclusion

Design outcomes

Primary

Measure	Time frame
Diagnostic accuracy of combination of CT perfusion and CT coronary angiography for detecting myocardial ischemia	—

Countries

Japan

Contacts

Public ContactChisato Kondo

Tokyo Women's Medical University Department of Diagnostic Imaging and Nuclear Medicine

kondo.chisato@twmu.ac.jp03-3353-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026