EPA-enriched dietary supplement to prevent reduction of lean body mass in patients with exacerbation of COPD : a randomized control trial

EPA-enriched dietary supplement to prevent reduction of lean body mass in patients with exacerbation of COPD : a randomized control trial - EPA-enriched supplementation therapy in patients with exacerbation of COPD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015805

Enrollment

Registered

2014-12-01

Start date

2014-11-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exacerbation of COPD

Interventions

EPA-enriched dietary supplement (ProSure) dietary supplement (Ensure H)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Clinical diagnosis of COPD, patients hospitalized for exacerbation of COPD or pneumonia. 2. Patients who are planned to receive pulmonary rehabilitation. 3. Patients who can take dietary supplement orally.

Exclusion criteria

Exclusion criteria: 1. Known severe allergy to any drugs 2. Patients in nutrition therapy with ProSure of ENCURE-H. 3. Patients regarded as inadequate to receive additional nutrition therapy due to severe diabetes and/or hyperlipidemia. 4. Patients who refuse pulmonary rehabilitation

Design outcomes

Primary

Measure	Time frame
Lean body mass index (LBMI) Skeletal muscle mass	—

Secondary

Measure	Time frame
Body mass index Physical activity COPD assessment test modified medical research council Plasma level of EPA prealbumin, albumin, total cholesterol, cholinesterase	—

Countries

Japan

Contacts

Public ContactTakashi Ogasawara

Hamamatsu medical center Department of respiratory medicine

shikatarawasagao@gmail.com0535437111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026