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The safe and effectiveness of continuous cisternal irrigation with artificial magnesium solution in patient with aneurysmal subarachnoid hemorrhage.

The safe and effectiveness of continuous cisternal irrigation with artificial magnesium solution in patient with aneurysmal subarachnoid hemorrhage. - Effects of continuous intracisternal magnesium injection for vasospam in subarachnoid hemorrhage.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000015760
Enrollment
70
Registered
2014-11-26
Start date
2008-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subarachnoid hemorrhage

Interventions

continuous cisternal irrigation with artificial magnesium solution ordinary treatment

Sponsors

Juntendo Univerisity Shizuoka Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aneurysmal subarachnoid hemorrhage 2. Patients treated by clipping via craniotomy within 72 hours after SAH 3. Patients classified as WFNS SHA Grade 1 to 4 4. Patients classified as Fisher CT group 2 and 3

Exclusion criteria

Exclusion criteria: 1. Age older than 80 years 2. Patients with severe surgical complication 3. Patients with pregnancy 4. Patients with malignant tumor, liver failure, and renal failure 5. Patients judged improper candidate by doctor

Design outcomes

Primary

MeasureTime frame
Functional outcome at 3months after onset (modified Rankin Scale, Glasgow outcome scale)

Secondary

MeasureTime frame
1. chronological changes of Mg2+ concentration in serum and CSF 2. infarction caused by vasospasm 3. MCA velocity measured by TCD 4. Angiographical vasospasm on digital subtraction angiography

Countries

Japan

Contacts

Public ContactTakuji Yamamoto

Junetndo University Shizuoka Hospital Department of Neurosurgery

tyamamoto@med-juntendo.jp055-948-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026