Oral hygiene
Conditions
Interventions
Ingestion of lactoferrin and lactoperoxidase-containing food for 8 weeks
Ingestion of placebo food for 8 weeks
Sponsors
Showa University, School of Dentistry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subjects aged over 65 years 2) Subjects have tongue coating
Exclusion criteria
Exclusion criteria: 1) Subjects who eat pureed or finely-chopped meal 2) Subjects whose nutrition has come from enteral feeding 3) Subjects who receive treatment of dental disease (except adjustment of denture, oral hygiene instruction) 4) Subjects with a history of allergy to milk 5) Subjects who had treatment with antibiotics in the past 1 month, or ones who are expected to have treatment with antibiotics 6) Subjects who consume food or oral care products which are used for preventing oral malodor or improving oral hygiene 7) Subjects who consume regularly lactoferrin or lactoperoxidase-containing food or oral care products 8) Subjects who have exacerbated disease of liver, kidney, heart, lung, gastro-intestine, blood, endocrine system, metabolic system
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Oral hygiene status | — |
Secondary
| Measure | Time frame |
|---|---|
| - The number of candida, periodontopathic bacteria, opportunistic bacteria and total bacteria in tongue coating and supragingival plaque - Experience effects | — |
Countries
Japan
Contacts
Public ContactTakafumi Ooka
Showa University, School of Dentistry Department of Special Needs Dentistry, Division of Hygiene and Oral Health
Outcome results
None listed