Optimal scan timing of single-phase computed tomography perfusion imaging for detecting myocardial ischemia: a derivation cohort from whole heart dynamic computed tomography perfusion imaging

Optimal scan timing of single-phase computed tomography perfusion imaging for detecting myocardial ischemia: a derivation cohort from whole heart dynamic computed tomography perfusion imaging - Optimal timing in single-phase myocardial CT perfusion

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000015700

Enrollment

Registered

2014-11-16

Start date

2013-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who give a full consent to this study. (2) angina (chest pain, documented ST-T change on electrocardiogram [ECG], or symptoms relieved by administration of nitroglycerin) (3) Asymptomatic patients with multiple coronary risk factors for CAD. (4) All patients perform ATP-stree dynamic myocardial CT perfusion, invasive coronary angiography and cardiac MRI within 30 days. no worsening angina symptom or cardiac events including revascularization therapy in the image session.

Exclusion criteria

Exclusion criteria: (1) acute/old myocardial infarction (clinical information) (2) cardiomyopathy (3) the left ventricular (LV) ejection fraction <20% (4) chronic atrial fibrillation (5) greater than first degree atrioventricular block (6) left complete bundle branch block (7) valvular heart disease (8) history of percutaneous coronary intervention and coronary artery bypass graft (9) unrecognized myocardial infarction assessed by late gadolinium enhancement (LGE) imaging.

Design outcomes

Primary

Measure	Time frame
Primary outcomes are the determination of the optimal scan timing of single-phase myocardial CTP imaging and the investigation of the diagnostic accuracy (sensitivity, specificity, positive and negative predictive value, accuracy) of the optimized single-phase myocardial CT perfusion imaging for detecting myocardial ischemia.	—

Secondary

Measure	Time frame
The peak CT attenuation and difference of time to peak between normal and ischemic segment are compared.	—

Countries

Japan

Contacts

Public ContactYuki Tanabe

Ehime University Graduate School of Medicine. Department of Radiology

yuki.tanabe.0225@gmail.com089-960-5371

Outcome results