Study to Determine the Optimal Starting Dose of FSH in a Low- Dose-Stepup Regimen

Study to Determine the Optimal Starting Dose of FSH in a Low- Dose-Stepup Regimen - Study to Determine the Optimal Starting Dose of FSH in a Low- Dose-Stepup Regimen

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015669

Enrollment

Registered

2014-11-17

Start date

2014-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

WHO group II ovarian failure (first-grade amenorrhea, oligomenorrhea, or anovulatory cycle), luteal phase insufficiency, or unexplained infertility

Interventions

At 50 IU if BMI is less than 20 kg/m2,Follicular growth will be monitored by transvaginal ultrasonography (US) on the 7th day of administration and every 2-4 days thereafter. In the absence of suffici

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) WHO group II ovarian failure (first-grade amenorrhea, oligomenorrhea, or anovulatory cycle), luteal phase insufficiency, or unexplained infertility 2) Written informed consent to the study given before enrollment

Exclusion criteria

Exclusion criteria: 1) WHO group I ovarian failure (second-grade [central] amenorrhea) 2) WHO group III ovarian failure (ovarian amenorrhea) 3) Hyperprolactinemia

Design outcomes

Primary

Measure	Time frame
Proportion of subjects whose dominant follicles grow to a mean diameter of 18 mm within 10 days after starting FSH administration and the cumulative FSH dose needed to reach this endpoint	—

Countries

Japan

Contacts

Public ContactToshiya Matsuzaki

Tokushima University Hospital Sub-Head of the Department of Obstetrics and Gynecology

matsuzaki.toshiya@tokushima-u.ac.jp0886313111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026