Drug therapies in older patients with glucocorticoid induced osteoporosis

Drug therapies in older patients with glucocorticoid induced osteoporosis - Drug therapies in older patients with glucocorticoid induced osteoporosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015660

Enrollment

200

Registered

2014-11-11

Start date

2010-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glucocorticoid induced osteoporosis

Interventions

alendronate sodium alendronate sodium + activated vitamin D

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age >65y 2. Receiving glucocorticoid for more than 3 months or planed to be received for more than 3 months 3. Starting prednisolone wiht more than 10mg /day

Exclusion criteria

Exclusion criteria: 1. eGFR<35ml/min or Cre<1.5mg/ml 2. Past history of urinary tract stone 3. Hyper- or hypoparathyroidism 4. Hyper- or hypothyroidism 5. Contraindication of alendronate or vitamin D 6. Warfarinization 7. Other conditions that an investigator assess as inappropriate 8.

Design outcomes

Primary

Measure	Time frame
proportions of symptomatic vertebral fracture	—

Countries

Japan

Contacts

Public ContactKei Ikeda

Chiba University Hospital Allergy and Clinical Immunology

K.Ikeda@faculty.chiba-u.jp043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026