Chronic kidney disease (CKD)
Conditions
Interventions
Protein restriction diet therapy (0.7 g/kg standard body weight/day) with low-protein rice for 24 weeks
Protein restriction diet therapy (0.7 g/kg standard body weight/day) without low-protein rice
Sponsors
Department of Clinical Nutrition Science, Niigata University Graduate School of Medical and Dental Sciences
Shinrakuen Hospital, Niigata Rinko Hospital, Nagaoka Red Cross Hospital, Nagaoka Chuo General Hospital, Tatchikawa General Hospital, Takeda General Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) CKD stages from G3aA2 to G4 in the KDIGO category 2) Those who have not used low-protein foods for the past one year 3) Body mass index of >20 and <27 kg/m2 4) Outpatients 5) Those at the age of 20 to 75 6) Those who have given written informed consent on the use of their data for the study
Exclusion criteria
Exclusion criteria: 1) Those with nephrotic syndrome 2) Those with polycystic kidney disease 3) Those with severe heart or liver disease 4) Those with pregnancy or at breast feeding 5) Those who are considered not eligible for the study by attending doctors due to any medical reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Covariance analysis of estimated protein intake per standard weight, adjusted by the intake at the start of the study | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Change of estimated energy intake 2) Change of renal functional parameters 3) Change of clinical nutritional parameters related to the criteria of protein energy wasting (PEW) 4) Change of parameters for phosphorus metabolism and metabolic acidosis 5) Change of parameters of quality of life (QOL) | — |
Countries
Japan
Contacts
Public ContactMichihiro Hosojima
Niigata University Graduate School of Medical and Dental Sciences Department of Clinical Nutrition Science
Outcome results
None listed