Research that focus on Multiliniage-differentiating stress enduring cells(Muse cells) for the treatment with mesenchymal stem cells in acute severe diseases

Research that focus on Multiliniage-differentiating stress enduring cells(Muse cells) for the treatment with mesenchymal stem cells in acute severe diseases - Research for Muse cells in acute severe diseases

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000015618

Enrollment

Registered

2014-11-07

Start date

2014-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis, trauma, burn, post-cardiac arrest syndrome, rhabdomyolysis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: a)Of the patients who were hospitalized in the Tohoku University Hospital Emergency center, trauma; Abbreviated Injury Score (AIS) 3 or more, burn; total burn surface area(TBSA) more than 10%, sepsis; severe sepsis, rhabdomyolysis; CK 5,000 or more, post-cardiac arrest syndrome; out-of-hospital cardiac arrest patients requiring hospital treatment with return of spontaneous circulation by resuscitation b)healthy person

Exclusion criteria

Exclusion criteria: Patients or family do not agree to participate in this study.

Design outcomes

Primary

Measure	Time frame
We evaluate the Muse cells in acute severe diseases. 1) Quantitative assessment of peripheral blood Muse cells: the quantification by flow cytometry, 2) Isolation of Muse cells, culture, form / function analysis In addition, it clarifies the association the dynamics of Muse cells with outcome, severity and damage-associated molecular patterns and inflammatory mediators.	—

Countries

Japan

Contacts

Public ContactTetsuya Sato

Tohoku University Graduate School of Medicine Division of Emergency and Critical Care Medicine

t23jor@med.tohoku.ac.jp022-717-7489

Outcome results