Asthma
Conditions
Interventions
During Treatment Period I (8 days
Visit 2, 3, 4), Impulse Oscillometry measurements are monitored over time (pre-dosing, at 0.5, 1, 2 hours post-dosing) before or after inhalation of Advair Diskus. During Treatment Period II (8 days
Visit 5, 6, 7), Impulse Oscillometry measurements are monitored as in Visit 2, 3, 4 after inhalation of Advair Aerosol.
During Treatment Period I (8 days
Visit 2, 3, 4), Impulse Oscillometry measurements are monitored over time (pre-dosing, at 0.5, 1, 2 hours post-dosing) before or after inhalation of Advair Aerosol. During Treatment Period II (8 days
Visit 5, 6, 7), Impulse Oscillometry measurements are monitored as in Visit 2, 3, 4 after inhalation of Advair Diskus.
Sponsors
Medical Corporation Fukuwakai Fukuwa clinic
THE DIVISION OF RESPIRATORY AND ALLERGY, DEPARTMENT OF INTERNAL MEDICINE
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Asthma and/or COPD outpatients with age more than 60 years irrespective of gender -Asthma and/or COPD outpatients with their PIF values of less than 90 L/min (including at least four patients with their PIF values of less than 60 L/min) -Patients who are prescribed Advair Diskus over the past four weeks in fixed doses
Exclusion criteria
Exclusion criteria: -Patients who use steroidal anti-inflammatory drugs -Patients who has developed respiratory infection in recent 6 weeks -Patients who are manifested by clinically abnormal laboratory values -Patients who are judged to be inappropriate as a subject by the clinical research director or the clinical research member
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variations in Impulse Oscillometry Measurements (R5-R20, X5, AX, Fres) from Baseline at Two Hours Post Dosing by Using Advair Diskus or Advair Aerosol and The Relationship with Peak Inspiratory Flow (PIF) | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy -Variations in Impulse Oscillometry Measurements from Baseline at Thirty minutes, One Hour, Two Hours Post Inhalation of Advair Diskus -Variations in Impulse Oscillometry Measurements from Baseline at Thirty minutes, One Hour, Two Hours Post Inhalation of Advair Aerosol -Comparison Values on Variations in Impulse Oscillometry Measurements from Baseline at Thirty minutes, One Hour, Two Hours Post Inhalation of Advair Diskus or Advair Aerosol Safety -Laboratory Values, Adverse Events etc. | — |
Countries
Japan
Contacts
Public ContactAbe, Kenji
Medical Corporation Fukuwakai Fukuwa clinic Statistics
Outcome results
None listed