Osteoporosis
Conditions
Interventions
once weekly teriparatide
alendronate
Sponsors
Research committee of A-TOP
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: A document agreement of the clinical study participation is provided and intends for a patient meeting all the following standards 1.Primary osteoporosis 2.a Japanese patient 75 years or older 3.postmenopausal women 4.The patient that an independence walk is possible 5.The patient who satisfies any of the following Patient with less than in bone density 60% of YAM or less than -3.3SD The patient who has vertebral body bone fractures more than two to the fourth lumbar vertebrae from the fourth thoracic vertebra at the time of registration Patient having a bone fracture of grade 3 The patient who has the past of the proximal thighbone bone fracture
Exclusion criteria
Exclusion criteria: 1.Secondary osteoporosis 2.bone loss Disease other than osteoporosis 3.diseases that affect the strength of the vertebral body 4.hypersensitivity 5.use of contraindicated therapeutic drugs 6.severe complications such as heart disease, liver disease, renal disease 7.problem with the reliability of the interview data 8.inpatient 9.Patients treated with teriparatide in the past
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of new vertebral fracture at 72 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of new vertebral fracture and non-vertebral fracture at 72 and 120 weeks Incidence of new vertebral fracture Exacerbation of vertebral fracture incidence BMD rate of change QOL rate of change Bone structure analysis | — |
Countries
Japan
Contacts
Public ContactYoji Mitadera
Public Health Research Foundation Comprehensive Support Project for
Outcome results
None listed