The patient with high grade multiple lugol voiding lesion(mLVL)s after endoscopic resection for early stage esophageal cancer
Conditions
Interventions
TS-1 administration for 6 months
Sponsors
Graduate School of Medicine, Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically proven early esophageal squamous cell carcinoma for primary tumor located in T1a or lower confirmed by pathological diagnosis 2)The grade of mLVLs are gradeC/D 3)The ulceration of endoscopic resection have healed 4)Aged 20<,no object for first or recurrence 5)PS=0,1,2 6)Adequate organ functions 7) Written informed consent
Exclusion criteria
Exclusion criteria: 1)Patients requiring for additional surgery or chemoradiotherapy for curatively treated with local therapy 2)Patients requiring chmotherapy or had chemothrapy past 6 months 3)Patients had irradiation of esophagus 4)Patients requiring Flucytosine administration 5)Patients requiring warfarine administration 6)Patients for allergy of iodine 7)Positive HBs antigen 8)Pregnancy, possible pregnancy after delivery or breastfeeding 9)Patients had complicating critical disease 10)Active infection requiring systemic therapy 11)contraindication for TS-1 12)Patients whom a researcher judges to be inappropriate as a subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion for improvement the grade of mLVLs | — |
Secondary
| Measure | Time frame |
|---|---|
| The cumulative incidence rate, the proportion for adverse event | — |
Countries
Japan
Contacts
Public ContactAkira Yokoyama, MD
Graduate School of Medicine, Kyoto University Department of Therapeutic Oncology
Outcome results
None listed