Higher brain dysfunction after traumatic brain injury: association with serotonin transporter deficiency.

Higher brain dysfunction after traumatic brain injury: association with serotonin transporter deficiency. - Serotonin transporter after traumatic brain injury.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015456

Enrollment

Registered

2014-11-30

Start date

2015-01-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatic brain injury

Interventions

Patients under cognitive rehabilitation for the treatment of chronic traumatic brain injury.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 20 years old. 2. Patients capable of a standard rehabilitation program. 3. Patients with written informed consent. 4. No contraindication for standard clinical imaging procedures (I-123 IMP SPECT, Brain MRI etc).

Exclusion criteria

Exclusion criteria: 1. Age less than 20 years old 2. Age equal or greater than 60 years od 3. Patients incapable of standard imaging or neuropsychological testing. 4. Patients with under neuropsychological medication before rehabilitation. 5. Higher brain dysfunction due to non TBI 6. Woman with possible pregnancy.

Design outcomes

Primary

Measure	Time frame
Functional association between higher brain function and serotonin transporter function.	—

Countries

Japan

Contacts

Public ContactNaoya Hattori

Hokkaido University Dept. of Molecular Imaging

nhattori@med.hokudai.ac.jp011-706-5152

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026