Exploratory trial to evaluate safety and efficacy of hydroxyapatite film formed by new dental treatment system for caries, dentin hypersensitivity or discolored tooth (investigator-initiated clinical trial)

Exploratory trial to evaluate safety and efficacy of hydroxyapatite film formed by new dental treatment system for caries, dentin hypersensitivity or discolored tooth (investigator-initiated clinical trial) - Exploratory trial to evaluate of hydroxyapatite film formed by new dental treatment system

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015439

Enrollment

Registered

2014-10-15

Start date

2014-11-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

caries, dentin hypersensitivity or discolored tooth

Interventions

formation of hydroxyapatite film

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Equal or more than 20 years old at the time of informed concent. 2. Agreement with written informed concent. 3. capable of going to the hospital regularly 4. Agreement with mixing investigational treatment and existing treatment 5. Agreement with selecting a tooth per a disease 6. Following selection criterion ?Caries: dentin caries ?Drntal hypersensitivity: pain induced by daily life ?Discolored tooth: hoping whitening

Exclusion criteria

Exclusion criteria: 1. Patients who have oral mucosal diseases 2. Past medical history about adverse effects of local anesthetic 3. Pregnancy or possibility of pregnancy 4. Participants of other clinical trial 5. Taking painkillers 6. Patients who are judged as in adequate for this trial by the investigators

Design outcomes

Primary

Measure	Time frame
pulpal response	—

Secondary

Measure	Time frame
morphological evaluation, secondary caries, gingival index, dental shade guide, satisfaction	—

Countries

Japan

Contacts

Public ContactRyo Akatsuka

Tohoku University Graduate School of Dentistry Division of Advanced Prosthetic Dentistry

akatsuka@dent.tohoku.ac.jp022-717-8369

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026