type 2 diabetes dementia
Conditions
Interventions
Sponsors
Kyoto Prefectural University of Medicine, Graduate School of Medical Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who are able to give written informed consent 2) Age is over 60 years and less than 85 years 3) MMSE score 24-27. 4) HbA1c 6.0-10.0% 5) Patients are able to do the following things in this trial - getting good compliance with consuming investigational food and coming to hospital
Exclusion criteria
Exclusion criteria: 1) Patients who did not agree with this study 2) Patients with severe renal dysfunction and severe hepatic dysfunction 3) Type 1 diabetes and other specific types of diabetes resulting from specific genetic syndromes, surgery, drugs, malnutrition, infections, and other illnesses 4) Patients treated with insulin 5) Patients with dementia or neurodegenerating disease 6) Patients who is taking drugs which affect the cognitive function 7) Patients who changed oral hypoglycemic drugs significantly 8) Patients who changed drugs which affect pH of interstitial fluid 9) Patients judged by the investigator to be ineligible for some other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| amyloid-beta, Tau protein, activity of the beta-amyloid converting enzyme 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| HbA1c, fasting plasma glucose, serum insulin, Mini-Mental State Examination | — |
Countries
Japan
Contacts
Public ContactShinobu Matsumoto
Kyoto Prefectural University of Medicine, Graduate School of Medical Science Department of Endocrinology and Metabolism
Outcome results
None listed