Prospective observational study about factors which influence the blood concentration of propofol during continuous infusion

Prospective observational study about factors which influence the blood concentration of propofol during continuous infusion - Study about the factors which influence the blood concentration of propofol during continuous infusion in ICU

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000015359

Enrollment

100

Registered

2014-10-07

Start date

2014-10-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients under sedation in ICU by continuous infusion of propofol

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients under sedation by continuous propofol infusion more than 24 hours at Kyushu University Hospital 2. Direct measurement of arterial pressure monitoring

Exclusion criteria

Exclusion criteria: 1. Hemoglobin<7 g/dL 2. Patients who is not appropriate to this study

Design outcomes

Primary

Measure	Time frame
The relationship between the blood concentration of propofol and genetic polymorphism (UGT1A9,CYP2B6), age, sex, blood pressure, liver function, kidney function etc.	—

Countries

Japan

Contacts

Public ContactTatsuya Yoshihara

Faculty of Medical Science, Kyushu University Department of Clinical Pharmacology

tatsuya@clipharm.med.kyushu-u.ac.jp092-642-6082

Outcome results