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The multicenter observational study for the prevalence of HIV-associated neurocognitive disorder (HAND) in Japan

The multicenter observational study for the prevalence of HIV-associated neurocognitive disorder (HAND) in Japan - J-HAND study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000015357
Enrollment
500
Registered
2014-10-08
Start date
2014-07-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV-associated neurocognitive disorder

Interventions

None listed

Sponsors

AIDS Clinical Center , National Center for Global Health and Medicine
Lead Sponsor
National Kyushu Medical Center Ehime University Hospital Kawasaki Medical School Hospital Niigata City General Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) HIV-infected patients (2) older than 20 years old (3) Japanese (4) Written informed consent

Exclusion criteria

Exclusion criteria: Active AIDS-defining disease. Congenital developmental retardation Definitive diagnosis of following diseases; Mental disorder, such as major depressive disorder, schizophrenia. Alzheimer's disease, Frontotemporallobar degeneration, Lewy-body disease, Vascular disease, Traumatic brain injury, Prion disease, Parkinson's disease, Huntington's disease. Another functional disorder (Epilepsy) Illegal substance use Severe alcoholism Endocrine disorder (hypothyroidism, Wernicke encephalopathy, Vitamin B12 deficiency) Current treatment or severe sequelae of CNS opportunistic infections Symptoms of a current, active infection a body temperature of >38.5 at the time of recruitment Experience of neuropsychiatric test within past 1 year Other inappropriate condition for neuropsychiatric test

Design outcomes

Primary

MeasureTime frame
The prevalence of HIV-associated neurocognitive disorder in Japan

Secondary

MeasureTime frame
The evaluation of risk and confounding factors for neuropsychiatric scores.

Countries

Japan

Contacts

Public ContactEi Kinai

National Center for Global Health and Medicine AIDS Clinical Center

ekinai@acc.ncgm.go.jp03-3202-7181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026