Treatment of vocal fold scar with KP-100LI: phase I/II clinical trial

Treatment of vocal fold scar with KP-100LI: phase I/II clinical trial - KP-100LI for vocal scar

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015337

Enrollment

Registered

2014-10-03

Start date

2014-10-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vocal fold scar, sulcus

Interventions

Transoral application of KP-100LI to the vocal fold

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosis of vocal fold scar or suclus by stroboscopic exmaination No orgnic or neurologic disorder on the vocal fold More than 11 scor of VHI-10

Exclusion criteria

Exclusion criteria: Airway disease caused by burn History of malignant diseases Pregnant woman Severe systemic diseases

Design outcomes

Primary

Measure	Time frame
Safty aspect for KP-100LI	—

Secondary

Measure	Time frame
Therapeutic effect in VHI-10, Jitter, MPT, GRBAS, NMWA	—

Countries

Japan

Contacts

Public ContactShigeru Hirano

Kyoto University Hospital Otolaryngology

hirano@ent.kuhp.kyoto-u.ac.jp075-751-3731

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026