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Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery

Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery - Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000015334
Enrollment
40
Registered
2014-10-03
Start date
2014-10-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

intravenous acetaminophen (1000mg) injection 15minutes before the end of surgery, and after 6 hours, 12hours postoperatively flurbiprofen (50mg) injection 15minutes before the end of surgery, and afte

Sponsors

Department of anesthesiology, Kumamoto university
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: a patient for elective partial mastectomy a 50-65 kilograms adult

Exclusion criteria

Exclusion criteria: past history of peptic ulcer eGFR under 60 ml/min an allergy to propionic acid-based NSAIDs an allergy to acetaminophen a pregnant woman past history of Aspirin-induced asthma liver cirrhosis contraindication to propofol

Design outcomes

Primary

MeasureTime frame
Postoperative pain evaluation performed by visual analog scale (VAS) after 3 hours, 6 hours and 24 hours postoperatively.

Countries

Japan

Contacts

Public ContactTakahiro Nonaka

Kumamoto university hospital Department of anesthesiology

end_of_uruma@yahoo.co.jp096-373-5275

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026