Healthy adults
Conditions
Interventions
Ingestion of bilberry extract for 12 weeks
Ingestion of placebo without bilberry extract for 12 weeks
Sponsors
TTC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Males and females from 20 to 64 years of age (2) Visual display terminal (VDT) user (3) Subjects with eye strain and eye dryness by VDT load
Exclusion criteria
Exclusion criteria: (1) Subjects who have history of the organic eye disease (e.g., cataract, glaucoma, diabetic retinopathy, and age-related macular degeneration) (2) Subject who are under medication for eye disease (e.g., eye fatigue and dry eye) (3) Subjects who have history of the autoimmune disease (e.g., Sjogren syndrome, Basedow's disease, Hashimoto's disease, rheumatoid arthritis) (4) Subjects who have a severe ametropia form result of screening test. (5) Strabismus (6) Subjects who routinely use quasi-drug, medicine, and/or health food containing bilberry extract. (7) Subjects who use eye drops (including behind-the-counter medicine) more than 4 days in a week (excluding artificial tears (e.g., Soft santear, artificial tear Mytear eye drop, and Mytear dry mini) (8) Subjects who routinely take health foods (e.g., lutein, zeaxanthin, multi-vitamins, multi-mineral, omega-3 fatty acids (DHA and EPA)), quasi-drug, or medicine related to eye wellness / or take them a month before start of this study (9) Subjects who have history or plan in study period to take punctual plug and punctual closing surgery (10) Subjects who have history of ophthalmic surgery (including LASIK) within 3 months before start of study or have a schedule of ophthalmic surgery in study period (11) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire (12) Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination (13) Subjects who can't carry out the VDT loading test during study period (14) Subjects who have possibility of allergy symptoms onset (15) Subject who are under treatment or have a history of needing medical treatment (16) Subjects who plan to go overseas more than one week during study period (17) Subjects who have participated in other clinical study (18) Subjects who are judged as unsuitable for the study by physician for any other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The scores and the total score of eye fatigue and dry eye symptoms of each questionnaire, in variation of before and after of VDT load | — |
Secondary
| Measure | Time frame |
|---|---|
| NEI VFQ-25, Scores and total score of eye fatigue and dry eye symptoms of each questionnaire of before or after of VDT load | — |
Countries
Japan
Contacts
Public ContactYoshiki Shimizu
TTC Co.,Ltd. Clinical Research Planning Department
Outcome results
None listed