Effects of exercise training on kidney function in patients with chronic kidney disease: A prospective multicenter study

Effects of exercise training on kidney function in patients with chronic kidney disease: A prospective multicenter study - CKD-Ex Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015276

Enrollment

200

Registered

2014-10-01

Start date

2014-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CKD patients

Interventions

Intervention group Frequency: Aerobic exercise training more than 3/week (include supervised aerobic exercise training more than 2/week) Time: 30-60min/day Intensity: aerobic threshold (AT) level c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Chronic kidney disease patients(CKD stage: G3a, G3b and G4) and not be applicable to exclusion criteria of exercise training recommended by guideline for Rehabilitation in Patients with Cardiovascular Disease (2012)

Exclusion criteria

Exclusion criteria: End stage renal failure with hemodialysis therapy, disable patients due to orthopedics or neuromuscular problem, active nephritis, patients with cognitive impairment, patients onset myocardial infarction, stroke, acute heart failure within 1 month or underwent cardiac surgery within 1 month, and keep stable condition at least 1 month, patients have possibility of use EPO during study period.

Design outcomes

Primary

Measure	Time frame
Etimated glomerular filtration rate (eGFR)	—

Secondary

Measure	Time frame
Urine protein, urinary albumin	—

Countries

Japan

Contacts

Public ContactMasakazu Saitoh

SAKAKIBARA HEART INSTITUTE HOSPITAL Department of Physiotherapy

msaitoh@shi.heart.or.jp042-314-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026