Evaluation of macular microcircular alteration induced by glaucoma topical drugs using high resolution scannning LASER ophthalmoscope (SLO)

Evaluation of macular microcircular alteration induced by glaucoma topical drugs using high resolution scannning LASER ophthalmoscope (SLO) - Evaluation of macular microcircular alteration induced by glaucoma topical drugs using high resolution scannning LASER ophthalmoscope (SLO)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015254

Enrollment

160

Registered

2014-09-25

Start date

2014-10-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with: glaucoma ocular hypertension

Interventions

To take images of the human ocular fundus using scannning LASER ophthalmoscope (SLO), laser speckle flowgraphy (LSFG), and optical coherence tomography (OCT) before and at 7days, 1 and 3months after s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient 1) Male or female older than 20 years-old 2) patients with glaucoma or ocular hypertension 3) Subjects who sign an informed consent form to participate in the clinical study

Exclusion criteria

Exclusion criteria: 1) Having any side-effects (hypersensitivity, rised intraocular pressure etc.) against mydriatics 2) Revealed narrow angle by slit-lamp examination 3) When a doctor accepted the middle-class above-mentioned cataract 4) Subjects who a doctor in attendance declares ineligible for any reason

Design outcomes

Primary

Measure	Time frame
Blood flow rate in macular capillaries before and at 7days, 1 and 3months after starting topical anti-glaucoma medications	—

Secondary

Measure	Time frame
Diameter of macular capillaries before and at 7days, 1 and 3months after starting topical anti-glaucoma medications	—

Countries

Japan

Contacts

Public ContactHideo Nakanishi

Kyoto University Graduate School of Medicine Ophthalmology & Visual Sciences

eye@med.kyoto-u.ac.jp+81-75-751-3248

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026