Major depressive disorder (monopolar depression) and bipolar disorder(bipolar I disorder and bipolar II disorder)
Conditions
Interventions
fMRI neurofeedback Connectivity-based neurofeedback using a 3T fMRI apparatus
Duration of intervention: 1 week to 2 weeks Dose of intervention: 6 to 10 sessions per day
Sponsors
Kyoto University
Advanced Telecommunications Research Institute International(ATR)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. DSM-IV-TR diagnosis of major depressive disorder or bipolar disorder(BPI or II) 2. Current diagnosis of major depressive episode 3. Normal visual acuity 4. Aged 20-65 years-old, outpatients, self-sustained ADL 5. Capability of informed consent
Exclusion criteria
Exclusion criteria: 1. Implanted cardiac pacemaker 2. Surgical aneurysm clips 3. Neurostimulator 4. Implanted pumps 5. Metal fragments in body/eyes 6. Tattoos or permanent eyeliner (if ink contains metallic specks) 7. Treatment history of ECT 8. Diagnosis of neurological disorders (including epilepsy), substance dependence, or significant cardiac disease 9. History of neurological disorders (including epilepsy), substance dependence, or head injury with loss of consciousness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Hamilton Depression Rating Scale (Ham-D) 17items and 24items 2) Beck Depression Inventry II (BDI-II) 3) Self-rating Depression Scale (SDS) | — |
Countries
Japan
Contacts
Public ContactJun Miyata
Kyoto University Graduate School of Medicine Department of Psychiatry
Outcome results
None listed