middle-aged female
Conditions
Interventions
Ingestion of a capsule including AG herb MIX once a day in fasting for 12 weeks
Ingestion of a placebo capsule including AG herb MIX once a day in fasting for 12 weeks
Sponsors
Karada Lab, Inc.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Healthy Japanese women ages 45 or more and less than 65 years old
Exclusion criteria
Exclusion criteria: 1)Diabetics receiving medication or who need treatment 2)Persons with food allergy 3)Patients with a history of serious liver, renal or heart disease 4)Persons with the skin chronic disease including atopic dermatitis 5)Smoking persons 6)Persons with less than five hours in mean sleep 7)Users of anti-glycation foods or cosmetics 8)Users of foods or supplements affecting blood glucose 9)Patients who might affect the test values during the study due to chronic diseases or acute diseases 10)Patients with food or medicine allergies 11)Patients who had surgery of the digestive tract 12) Patients suspected of chronic or acute infectious diseases 13) Persons with high BMI more than 30 14)Persons who participated in other clinical trials within one month before start of this examination 15)Persons who have a difficulty in keeping their habits and customs 16)Persons who have a difficulty keeping a life diary 17)During the pregnancy or persons nursing and persons who may be pregnant 18)Persons who had donated > 200 mL of blood within 1 month or > 400 mL within 3 months prior to the study 19)Persons who work for anti-glycation foods related companies, or persons who have family members working for such companies 20)Persons who may eat or drink too much during this trial , or who have a habit of eating out 21)Persons who have been judged to be inappropriate for the study by a human medical trial supervisor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin elasticity, skin carboxymethylysine, skin AGEs accumulation, carboxymethylysine, 3-deoxyglucosone | — |
Secondary
| Measure | Time frame |
|---|---|
| skin color, skin image analysis by VISIA, fasting plasma glucose, HbA1c, insulin, questionnaire( the Anti-Aging QOL Common Questionnaire, skin questionnaire) | — |
Countries
Japan
Contacts
Public ContactHiroshige Kawai
Karada Lab, Inc. no division
Outcome results
None listed