non-dialysis chronic kidney disease
Conditions
Sponsors
Wakayama Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients of filling the following all criteria and having ability for agreement 1) Chronic kidney disease stage G3-G4 (15 mL/min/1.73m2<=GFR<60 mL/min/1.73m2) 2) Hyperphosphatemia patients without receiving phosphate binder treatment (serum phosphate>4.5 mg/dL) 3) Available for follow-up for at least 1 year in the opinion of the investigator
Exclusion criteria
Exclusion criteria: 1)<20years old 2)Malignancy of any type 3)Contraindications to lanthanum carbonate 4)Diabetes mellitus 5)Renal transplant 6)Pregnant or breast-feeding women 7)Ineligible patients for this study according to the investigator's judgment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline and compare between 2 groups, as follow items : FGF23, alfa-Klotho and sclerostin (at 2 months) | — |
Secondary
| Measure | Time frame |
|---|---|
| Change from baseline and compare between 2 groups, as follows: Phosphate, Calcium, Phosphate excretion in urine, iPTH, wPTH (at 2 months) delta-FGF23, eGFR, 1/Cr, Cr, iPTH, wPTH, BAP, TRACP-5b, OPG, Mg (at 12 months) | — |
Countries
Japan
Contacts
Public ContactMasaki Ohya
Wakayama Medical University Division of Nephrology
Outcome results
None listed