Can Modulation of neurochemical pathways in the brain reverse the effects of sleep deprivation on the psychmotor and cognitive performance of surgical trainees 09/H0304/24 amendment 5(REC6)

Can Modulation of neurochemical pathways in the brain reverse the effects of sleep deprivation on the psychmotor and cognitive performance of surgical trainees 09/H0304/24 amendment 5(REC6) - The Preservation of Cued Recall in the Acute Mentally Fatigued State- A Randomised Crossover Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015219

Enrollment

Registered

2014-09-22

Start date

2012-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A randomised crossover study involving twenty healthy medical students assessed free (presentation) and cued (MCQ) recall of clinical case histories at 0 and 2hrs under low and high cognitive load settings using the N-Back task.

Interventions

Day 1 N-Back task - visual 1-back for 15 minutes alternating with 15 minutes rest time for 90 minutes. (control). Using History 1 Day 2 N-Back task - dual 2 back (visual and audio) for 90 minutes Us

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy medical students with experience of presenting clinical histories. Stimulant (caffeine) free from midnight No regular medications

Exclusion criteria

Exclusion criteria: Caffeine based products, chocolate or medications that would effect cognitive state.

Design outcomes

Primary

Measure	Time frame
Free Recall Cued Recall	—

Secondary

Measure	Time frame
N-Back task Visual analogue scale Stanford Scale NASA TLX	—

Countries

Europe

Contacts

Public ContactAra Darzi

Imperial College London Department of BioSurgery and Surgical Technology

a.darzi@imperial.ac.uk442033126666

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026