non small cell lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) planning to treat with paclitaxel and nob-paclitaxel. 2) 20 years old or more 3) no neuropahty before enrollment 4) controlled diabetes mellitus (DM) or no DM 5) no significant skin disorder of extremities
Exclusion criteria
Exclusion criteria: 1) any grade of neurotoxicity 2) no ability to express toxicity 3) significant skin disorder of extremites 4) symptomatic brain metastasis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of peripheral neuropathy in the third cycle before starting | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) period to development of neurotoxicity (grade 2 or more) 2)proportion of cases who experience contra-lateral neuropathy previous to intervention side. 3) grade of neuropathy 4)relationship among proportion of neuropathy and proportion of completion and effect of chemotherapy. 5) safety of compression gloves and compression stockings. | — |
Countries
Japan
Contacts
Miyagi Cancer Center respiratory medicine