The effect of leucine high formulated nutritional supplementation on physical function, skeletel muscle mass and muscle strengh with resistance traiing for inpatient disabled elderly in convalescent rehabilitation - a randomized controlled trial

The effect of leucine high formulated nutritional supplementation on physical function, skeletel muscle mass and muscle strengh with resistance traiing for inpatient disabled elderly in convalescent rehabilitation - a randomized controlled trial - The effect of leucine high formulated nutritional supplementation on physical function

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015158

Enrollment

Registered

2014-09-16

Start date

2014-09-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopenia with disability

Interventions

1.Leucin high formulated nutritional supplement 2.Group sit-stand trainig 1.Group sit-stand trainig

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Elderly patients aged 65 yo and over hospitalized in a rehabilitation ward 1.Undergoing group stand-sit training 3.Appropriate nutritional management 4.Able to start group stand-sit training

Exclusion criteria

Exclusion criteria: 1.Disturbance of consciousness 2.Severe dementia 3.Disability of oralintake 4.Severe renal dysfunction 5.Medically considered inappropriate condition

Design outcomes

Primary

Measure	Time frame
The change in Physical activity. Measured by Functional Independence Measure (FIM)	—

Secondary

Measure	Time frame
1.Muscle mass (Skeletal muscle mass index detected using BIA, AMA,AC,AMC,CC measured by anthropometric method) 2.Muscle strength (hand grip strengh) 3.Nutritional assessment (MNA-SF,BMI,Alb,Hb,T-Cho,TLC,BUN,Cr,vitamin-D,CRP,body cell mass) 4.Plasma free amino acid profile 5.25(OH)D	—

Countries

Japan

Contacts

Public ContactYoshihiro Yoshimura

Kumamoto Rehabilitation Hospital Medical office

hanley.belfus@gmail.com0962323111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026