Development of novel biomarkers of neurodegenerative diseases-comprehensive analysis of the proteins and the RNAs in exosomes extracted from cerebrospinal fluid and urine

Development of novel biomarkers of neurodegenerative diseases-comprehensive analysis of the proteins and the RNAs in exosomes extracted from cerebrospinal fluid and urine - Development of novel biomarkers in exosomes extracted from cerebrospinal fluid and urine

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015133

Enrollment

130

Registered

2014-09-12

Start date

2014-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurodegenerative diseases including amyotrophic lateral sclerosis, Parkinson disease, multiple system atrophy, progressive supranuclear palsy, corticobasal syndrome

Interventions

Examination of cerebrospinal fluid and urine will be conducted, but no interventions are planned.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects are the patients having neurodegenerative diseases (such as amyotrophic lateral sclerosis, Parkinson disease, multiple system atrophy, progressive supranuclear palsy or corticobasal syndrome) and other diseases, who are required to have examination of cereblospinal fluid and urine. 20 patients of each neurodegenerative disease and 30 patients with other disease will be attended.

Exclusion criteria

Exclusion criteria: The participants are not limited by the age or gender.

Design outcomes

Primary

Measure	Time frame
Identification of novel biomarkers	—

Countries

Japan

Contacts

Public ContactHiroshi Doi

Yokohama City University Department of Neurology and Stroke Medicine

doi@rkd.d-bs.com045-787-2511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026