Dementia of the Alzheimer type
Conditions
Interventions
On the first day, subjects receive training of the object recognition behavior task and the paired-associate learning task. On the 8th day, they take Betahistine and take tests of the object recognit
Sponsors
Kyoto University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Informed consent for study participants must be obtained from the subjects themselves 2) Over 20 years old and less than 50 years old (at the time of registration) 3) Normal or corrected vision
Exclusion criteria
Exclusion criteria: 1) Active peptic ulcer, bronchial asthma, pheochromocytoma, Meniere's disease, Meniere's syndrome, vertigo, blood disorders, liver failure, kidney failure, and severe mental illness 2) History peptic ulcer, drug dependence, alcoholism, etc. 3) Administration of the drug within a week before the test 4) Pregnant or being suspected females, breast-feeding, males/females who do not agree to the terms of contraception during the study 5) Drinking a fruit juice containing grapefruit, orange, or apple, between the first day and the 8th day in the test period 6) Participated in the Phase 1 clinical trials of new drug substances and received the drug dosing within four months before the test 7) Seropositive of HBs antigen, HCV antibody, HIV antigen-antibody, syphilis serum (TP antibody, RPR method) 8) History of allergies to food or drugs 9) A person who was judged by investigator as an inappropriate subject of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate performance of the object recognition behavior task and the paired-associate learning task | — |
Countries
Japan
Contacts
Public ContactMIZUTA Hiroto
Kyoto University Graduate School of Medicine Department of Psychiatry
Outcome results
None listed