Type 2 diabetes mellitus
Conditions
Interventions
SGLT2 inhibitors: This study to examine the change in SD of 24h and MAGE by CGM,blood glucose levels,Body weight,urine volume before and after the start.
DPP-4 inhibitors: This study to examine the
Sponsors
Yokohama City University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)before test registration - the meal and exercise cure for one month or more or a meal and an exercise cure, and diabetic medicine and inpatient 2)HbA1c(NGSP):more than 7.0%, less than 14.0% 3)126mg/dl<=FPG<250mg/dl and 200mg/dl<=PPG<350mg/dl 4)eGFR more than 45ml/min/1.73m 2 5)Type 2 diabetes 6)Pts with written IC 7)Age more than 20, less than 85
Exclusion criteria
Exclusion criteria: 1)severe ketosis, diabetic coma within 6 months 2)severe infection, before operation, severe trauma 3)severe hepatic dysfunction 4)or severe renal dysfunction (Cr: more than 1.5mg/dl) 5)Patients who use of insulin 6)pregnacy 7)Allergy for sitagliptin, nateglinide,liraglutide and exenatide 8)Patients judged by the investigator to be ineligible for some other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SD of blood glucose by CGM | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)averate blood glucose, MAGE by CGM 2)FPG and PPG at 1, 2, 3, 4, 5, 6, 7 days of treatment 3)%chagne of FPG, HbA1c,IRI,CPR, a from baseline 4)a questionnaire survey | — |
Countries
Japan
Contacts
Public ContactJoe Nagakura
Yokohama City University Medical Center Department of Endocrinology and Diabetes
Outcome results
None listed