Selective bladder preservation with curative intent consisting of chemoradiotherapy plus partial cystectomy for muscle-invasive bladder cancer

Selective bladder preservation with curative intent consisting of chemoradiotherapy plus partial cystectomy for muscle-invasive bladder cancer - Bladder preservation consisting of chemoradiotherapy plus partial cystectomy for muscle-invasive bladder cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015076

Enrollment

200

Registered

2014-09-12

Start date

2008-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle-invasive bladder cancer

Interventions

Low-dose chemoratiation therapy Partial cystectomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Muscle-invasive bladder cancer (cT2-3N0M0) No involvement of the bladder neck Response to induction chemoradiation therapy

Exclusion criteria

Exclusion criteria: CIS Unfit for low-dose chemoradiation therapy or radical surgery under general anesthesia due to complications

Design outcomes

Primary

Measure	Time frame
Muscle-invasive bladder cancer-free survival in patients with bladder preservation	—

Secondary

Measure	Time frame
Cancer specific survival, Overall survival, Recurrence-free survival, bladder preservation rate, QOL in patients with bladder preservation, Clinical and pathological effect of TURBT + low-dose chemoradiation	—

Countries

Japan

Contacts

Public ContactYasuhisa Fujii

Tokyo Medical and Dental University Urology

y-fujii.uro@tmd.ac.jp03-5803-5295

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026