Effects of hot spring water drinking and/or bathing on the human physiological homeostasis

Effects of hot spring water drinking and/or bathing on the human physiological homeostasis - ONSEN - Metabolome

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015045

Enrollment

200

Registered

2014-09-03

Start date

2014-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medicine in general

Interventions

Drinking and/or bathing hot spring water

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Who does not drink and/or bathe hot spring water in daily

Exclusion criteria

Exclusion criteria: Who have habit drink and/or bathe hot spring water in daily

Design outcomes

Primary

Measure	Time frame
Metabolome analysis of plasma, urine and feces Gut microbiome analysis Subjective status (Visual Analog Scale) Gastrointestinal Symptom Rating Scale Mood Check List - Short Form	—

Secondary

Measure	Time frame
Weight Blood pressure Waist size Blood test (urinary acid, blood glucose in serum, glycoalbumin, insulin, NaCl, Ca, Mg, cortisol, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, blood glucose in plasma (morning fasting sample), HOMA-R(morning fasting sample))	—

Countries

Japan,Asia(except Japan)

Contacts

Public ContactShinnosuke Murakami

Keio University Institute for Advanced Biosciences

mushin@sfc.keio.ac.jp+81-235-29-0528

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026