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Is profound muscle relaxation necessary for laparoscopic surgery?

Is profound muscle relaxation necessary for laparoscopic surgery? - Is profound muscle relaxation necessary for laparoscopic surgery?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000015028
Enrollment
88
Registered
2014-09-03
Start date
2014-09-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholelithiasis

Interventions

General anesthesia is induced propofol 2mg/kg and remifentanil 0.5 microgram/kg/min IV. After calibration of the TOF-Watch, rocuronium 0.6mg/kg is injected to facilitate tracheal intubation. Anesthesi
2, a bolus dose of rocuronium 0.1mg/kg is administrated. Target TOF count is 1 to 2. During the laparoscopic procedure, the surgeon scored the surgical working conditions at 20 min intervals according
2, a bolus dose of rocuronium 0.2mg/kg is administrated. Target PTC is 0 to 2. During the laparoscopic procedure, the surgeon scored the surgical working conditions at 20 min intervals according to a

Sponsors

Tokyo Metropolitan Tama Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients scheduled for elective laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: neuromuscular disease, allergy to medication to be used during anesthesia, significant liver or renal dysfunction, apoplexy, a body mass index of >30, inability to give informed consent.

Design outcomes

Primary

MeasureTime frame
The proportion of overall excellent relaxation. The patient's condition is described as overall excellent relaxation if all the scores obtained are 4. Surgical conditions are assessed by surgeons using a four-point surgical rating scale.

Secondary

MeasureTime frame
Mean surgical rating score, mean intraabdominal pressure, the proportion of operations completed at pneumoperitoneum 8 mmHg, the number of times of additional dosage of rocuronium in case of inadequate surgical conditions.

Countries

Japan

Contacts

Public ContactTakaya Hojo

Tokyo Metropolitan Tama Medical Center Department of Anaesthesia

ha_hi_hu_he_hojo@yahoo.co.jp042-323-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026