A randomized control trial of Trapa japonica extract intake on anti-glycation effect and improvement in skin.

A randomized control trial of Trapa japonica extract intake on anti-glycation effect and improvement in skin. - Anti-glycation effect of "Trapa japonica extract" on human skin.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000015011

Enrollment

Registered

2014-09-01

Start date

2014-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy men and women

Interventions

Test group Oral intake of capsules with 100mg Trapa japonica extract before breakfast for 12 weeks Control group Oral intake of capsules without Trapa japonica extract before breakfast for 12 week

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy Japanese men and women ages 20 or more and less than 70 years old

Exclusion criteria

Exclusion criteria: 1) Users of anti-glycation materials 2) Users of medicines or supplements affecting blood glucose 3) Persons with severe dysfunction of liver, kidney or heart 4) Persons with food allergy or allergic dermatitis 5) Persons who received gastrointestinal surgery

Design outcomes

Primary

Measure	Time frame
Skin elasticity, corneum CML, skin AGEs accumulation, fasting plasma glucose, glycoalbumin, HDL-C, LDL-C, trglyceride, questionnaire	—

Countries

Japan

Contacts

Public ContactYoshika Ishioka

Graduate School of Life and Medical Sciences, Doshisha University Anti-Aging Medical Research Center

ishiyoshi.2.13@gmail.com0774-65-6382

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026