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Examination of non-cholesterol sterols as the biomarkers for insulin resistance and inflammation

Examination of non-cholesterol sterols as the biomarkers for insulin resistance and inflammation - Non-cholesterol sterols as markers for insulin resistance and inflammation

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000015010
Enrollment
300
Registered
2014-09-01
Start date
2014-09-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes, normal subject

Interventions

None listed

Sponsors

Fukushima Medical University, Aizu Medical Center Department of Metabolism, Diabetes and Nephrology
Lead Sponsor
Fujitsu Semiconductor Company, Aizuwakamatsu Factory
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Those who are not taking anti-hyperlipidemic medicine. Those who are not under insulin therapy.

Exclusion criteria

Exclusion criteria: Those who suffer from critical illness (liver diseases, kidney diseases, heart diseases, malignancies, etc.) Those who suffer from collagen diseases. Those who suffered from acute inflammatory diseases during the past 2 weeks. Those who are pregnant, breast-feeding, or have the probability of pregnancy. Those whose HbA1c values are more than 7.5%.

Design outcomes

Primary

MeasureTime frame
First, we measure the levels of several sterols with FPLC using human plasma samples. Then, we will analyze the association of these sterol values with the markers for insulin resistance (HOMA-IR, adiponectin levels, etc) and the markers for inflammation (high sensitive CRP, TNFa, bioactive phospholipids, etc).—

Countries

Japan

Contacts

Public ContactKazuhisa Tsukamoto

Fukushima Medical University, Aizu Medical Center Department of Metabolism, Diabetes and Nephrology

kazuhisatky@gmail.com0242-75-2100

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026