Development of treatment effect prediction method of oral appliance therapy for obstructive sleep apnea syndrome

Development of treatment effect prediction method of oral appliance therapy for obstructive sleep apnea syndrome - Development of treatment effect prediction method of oral appliance therapy for obstructive sleep apnea syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000014984

Enrollment

Registered

2014-08-28

Start date

2012-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who have received Oral appliance therapy in our hospital, and from whom is written informed consent is obtained in this study 2. Patients who have more than 20 teeth (including the residual anterial teeth) 3. The amount of mandible protrusion is more than 8mm

Exclusion criteria

Exclusion criteria: 1. Patients who have chronic nasal congestion, a high degree of tonsillar hypertrophy 2. Patients who will be received combined OA and nCPAP therapy 3. Patients who have received drug therapy related sleep (hypnotic, anxiolytic) 4. Diagonsed as mental disorders or temporomandibular disorders. 5. Patients who have a complication or history of respiratory disease. 6. Patients who have an allergy against steroids or vasoconstrictor. 7. Patients who need dental treatment for caries and periodontal disease in oral cavity

Design outcomes

Primary

Measure	Time frame
Respiratory resistance value, Apnea Hypopnea Index (AHI), LowestSpO2	—

Secondary

Measure	Time frame
Cephalometric radiograph, Subjective daytime sleepiness (JESS), Subjective sleep quality(PSQI)	—

Countries

Japan

Contacts

Public ContactShusuke Inukai

Tokyo Medical and Dental University Graduate school of Medical and Dental Sciences, Removable partial prosthodontics

shu.inukai.rpro@tmd.ac.jp03-5803-5515

Outcome results