Clinical study on the effect of antibacterial eye drops during administration of anti-VEGF drugs

Clinical study on the effect of antibacterial eye drops during administration of anti-VEGF drugs - Study on the Effectiveness of Antimicrobial Eye Drops During Anti-VEGF Drug Administration

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014964

Enrollment

Registered

2014-08-27

Start date

2014-08-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AMD and RVO

Interventions

Levofloxacin eye drop 1.5% Levofloxacin eye drop 1.5% and Cefmenoxime hydrochloride eye drop 0.5% in turn

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients scheduled for intravitreal injection consecutive 3 times every 1 month 2)20 years of age or more

Exclusion criteria

Exclusion criteria: 1)Patients with history of hypersensitivity or severe side effects on drugs using this study 2)Patients with history of intravitreal injection 3)Patients with history of antibiotics treatment within 3 months 4)Patients with history of ocular surgery within 6 months 5)Patients with heavy immune deficiency, atopic dermatitis, and diabetes 6)Patients with lacrimal duct obstruction 7)Patients whom investigators estimate are not eligible

Design outcomes

Primary

Measure	Time frame
Disinfection rate and drug sensitivity (0 month, 2 month, 3 month and 6 month) Changes in disinfection rate and drug sensitivity (0 month, 2 month, 3 month and 6 month) Incidence of postoperative endophthalmitis	—

Countries

Japan

Contacts

Public ContactYoshihiro Wakabayashi

Tokyo medical university hospital Department of ophthalmology

wbaki@tokyo-med.ac.jp03-3342-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026