Prospective cohort study of rheumatoid arthritis and Sjogren's syndrome (Prevention against the development of rheumatoid arthritis, through application of musculoskeletal ultrasonography and treatment for periodontal disease, collaboration with Kanazawa, Chiba and Nagasaki University

Prospective cohort study of rheumatoid arthritis and Sjogren's syndrome (Prevention against the development of rheumatoid arthritis, through application of musculoskeletal ultrasonography and treatment for periodontal disease, collaboration with Kanazawa, Chiba and Nagasaki University - Early arthritis cohort against the development of rheumatoid arthritis, association with periodontal disease, collaboration with Kanazawa, Chiba and Nagasaki University,

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014886

Enrollment

250

Registered

2014-09-01

Start date

2015-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early arthritis

Interventions

Introduce patients to the dentists to confirm the presence of periodontal disease,then the treatment is performed according to severity of periodontal disease. The information of musculoskeletal u

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients provided a signed consent form to participate in the study, which is approved by the each institutional review board 2. Patients with early arthritis disease duration less than 6 months.

Exclusion criteria

Exclusion criteria: 1. Under twenty years old 2. Non-RA rheumatic diseases

Design outcomes

Primary

Measure	Time frame
Exploratory study using blood, saliva, plaque:to examine the humoral factors and cell subsets from blood, and the humoral factors,autoantibodies and bacteria (number,types,etc)from saliva and plaque, suspected to relate with the pathogenesis of RA.	—

Countries

Japan

Contacts

Public ContactMami Tamai

Nagasaki University Hospital First department of internal medicine

tamai-ngs@umin.ac.jp095-819-7262

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

Prospective cohort study of rheumatoid arthritis and Sjogren&#39;s syndrome (Prevention against the development of rheumatoid arthritis, through application of musculoskeletal ultrasonography and treatment for periodontal disease, collaboration with Kanazawa, Chiba and Nagasaki University