Analysis of relationship between chronic periodontitis and glucose metabolic parameters (Ehime Dental Diabetes Study)

Analysis of relationship between chronic periodontitis and glucose metabolic parameters (Ehime Dental Diabetes Study) - Analysis of relationship between chronic periodontitis and glucose metabolic parameters (Ehime Dental Diabetes Study)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000014877

Enrollment

1000

Registered

2014-08-18

Start date

2011-06-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, chronic periodontitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: * Outpatients. * Cases from whom informed consent was obtained. * Genetic examination will be performed when informed consent, approved by the institutional review board, is obtained.

Exclusion criteria

Exclusion criteria: Cases judged inappropriate by the physician or dentist in charge.

Design outcomes

Primary

Measure	Time frame
Cytokines: inflammation parameters relating diabetes and chronic periodontitis such as TNF-alpha and resistin. Endotoxin relating substances: Lipopolysaccharide (LPS), LPS binding protein (LBP), CD14 Glucose metabolic parameters: glucose, insulin, HbA1c Oral function: number of remaining teeth, occlusion, taste, cleanliness Periodontitis: severity, quantification of periodontitis bacterium Gene SNPs: diabetes, HLA	—

Measure

Time frame

Cytokines: inflammation parameters relating diabetes and chronic periodontitis such as TNF-alpha and resistin. Endotoxin relating substances: Lipopolysaccharide (LPS), LPS binding protein (LBP), CD14 Glucose metabolic parameters: glucose, insulin, HbA1c Oral function: number of remaining teeth, occlusion, taste, cleanliness Periodontitis: severity, quantification of periodontitis bacterium Gene SNPs: diabetes, HLA

—

Countries

Japan

Contacts

Public ContactHiroshi Onuma

Ehime University Graduate School of Medicine Department of Diabetes and Molecular Genetics

onuma@m.ehime-u.ac.jp089-960-5647

Outcome results