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A pilot study on the safety and the efficacy of dose escalation in stereotactic body radiotherapy for the lung tumor

A pilot study on the safety and the efficacy of dose escalation in stereotactic body radiotherapy for the lung tumor - Dose escalation study in stereotactic body radiotherapy for the lung tumor

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000014815
Enrollment
35
Registered
2014-09-01
Start date
2014-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

Dose escalation in radiotherapy

Sponsors

Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Primary or metastatic lung cancer A. Primary lung cancer; Tumor size </=5cm, and clinical stage IA or IB B. Metastatic lung cancer; Tumor size </=5cm, two lung lesions or less, and no lesions other than lung 2) Those who are inoperable or who refuse surgery 3) Dose to adjacent organ is not estimated to exceed constraints in pretreatment chest CT 4) Patients' age must be>/=20 years old 5) ECOG performance status must be 0-2 6) Patients can lay on their back holding their arms over the heads, and keep that position at least 30 minutes

Exclusion criteria

Exclusion criteria: 1) previous irradiation around the lesion 2) With active interstitial pneumonia or pulmonary fibrosis 3) With severe diabetic mellitus or collagen disease 4) Women during pregnancy or lactating , or who might be pregnant 5) With psychiatric illness which impede protocol treatment 6) Patients who are considered to be inappropriate for this study by physicians

Design outcomes

Primary

MeasureTime frame
incidence of adverse effect

Countries

Japan

Contacts

Public ContactTakamasa Mitsuyoshi

Kyoto University Hospital Department of Radiation Therapy

mitsu.t@kuhp.kyoto-u.ac.jp075-751-3762

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026