Effects of Low Density Lipoprotein adsorption treatment on Arteriosclerosis obliterates(ASO)

Effects of Low Density Lipoprotein adsorption treatment on Arteriosclerosis obliterates(ASO) - Effects of LDL adsorption treatment on ASO

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014762

Enrollment

Registered

2014-08-11

Start date

2014-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral artery disease, Arteriosclerosis obliterans, End-stage renal disease on hemodialysis

Interventions

LDL adsorption treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The ESRD patients on hemodialysis who fulfilled the following criteria: 1. Ages from 20 years old, 2. Classified as > Fontaine class II, 3. Resistant to medication and/or difficult to perform PTA and/or bypass surgery. 4. The SPP value of one of measured regions is below 50 mmHg.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Who cannot interrupt an angiotensin converting enzyme inhibitor. 2.Judged as unsuitable from other reasons.

Design outcomes

Primary

Measure	Time frame
1. Signs , symptoms (wound healing, Fontaine classification, dose reduction of analgesics, intermittent claudication) 2. Blood flow (ABI, baPWV, SPP/lying position and sitting position)	—

Secondary

Measure	Time frame
1. Serum lipid (total cholesterol, HDL, triglyceride, remnant-like lipoprotein choresterol). 2. Blood test ( number of blood cells, CRP, HbA1c etc.)	—

Countries

Japan

Contacts

Public ContactShigeo Negi

WAKAYAMA MEDICAL UNIVERSITY Division of Nephrology, Department of Internal Medicine

shigeon@wakayama-med.ac.jp073-441-0639

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026