Detection of chemotherapy induced cardiac TOXicity in breast cancer study

Detection of chemotherapy induced cardiac TOXicity in breast cancer study - DETOX Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000014741

Enrollment

100

Registered

2014-08-01

Start date

2014-08-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with breast cancer undergoing anthracycline chemotherapy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with breast cancer undergoing anthracycline chemotherapy in the Kyoto University Hospital from 2014 to 2015.

Exclusion criteria

Exclusion criteria: Patients who declined to participate in the study.

Design outcomes

Primary

Measure	Time frame
Incidence of cardiotoxicity defined as a reduction of left ventricular ejection fraction >=5% to <55% with symptoms of heart failure or an asymptomatic reduction of left ventricular ejection fraction >=10% to <55%.	—

Secondary

Measure	Time frame
cardiac biomarkers echocardiographic parameters symptoms and signs of heart failure heart failure admission usage of cardioprotective drugs	—

Countries

Japan

Contacts

Public ContactKenji Nakatsuma

Kyoto University Hospital Department of Cardiovascular Medicine

kj1004@kuhp.kyoto-u.ac.jp0757514255

Outcome results