Clinical trial of effectiveness of Citrus unshiu juice enriched with beta-cryptoxanthin, vitamin E and zinc for nonalcoholic fatty liver disease

Clinical trial of effectiveness of Citrus unshiu juice enriched with beta-cryptoxanthin, vitamin E and zinc for nonalcoholic fatty liver disease - Clinical trial of effectiveness of Citrus unshiu juice enriched with beta-cryptoxanthin, vitamin E and zinc for NAFLD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014736

Enrollment

Registered

2014-08-01

Start date

2014-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nonalcoholic fatty liver disease

Interventions

enriched with beta-cryptoxanthin, vitamin E and zinc enriched with beta-cryptoxanthin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All subjects provide written informed consent All subjects are histologically diagnosed as NAFLD All subjects are over 20 years old, any sexuality and body mass index In subjects with diabetes mellitus concentration levels of FPG are under 140mg/dl and levels of HbA1c are under 7.0%

Exclusion criteria

Exclusion criteria: Patients with any other liver injury

Design outcomes

Primary

Measure	Time frame
Improvement of serum biochemical parameters (liver enzyme) about NAFLD	—

Secondary

Measure	Time frame
Improvement of chronic inflammation and anti-oxidant	—

Countries

Japan

Contacts

Public ContactBunzo Matsuura

Ehime University Graduate School of Medicine Lifestyle-related Medicine and Endocrinology

bmatsu@m.ehime-u.ac.jp089-960-5308

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026