Skip to content

Efficacy and safety of corneal crosslinking using KXL for keratoconic eyes

Efficacy and safety of corneal crosslinking using KXL for keratoconic eyes - Corneal crosslinking using KXL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000014719
Enrollment
10
Registered
2014-08-01
Start date
2013-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus

Interventions

Sponsors

Department of Ophthalmology, Ichikawa General Hospital, Tokyo Dental College
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Those who reveal all of following factors; 1. Keratoconus or keartectasia pattern by corneal topography/tomography 2. Thinnest corneal thickness is 400 um or more. 3. Progression of keratoconus in recent 2 years by corneal topography/tomography and/or manifest refraction. Progression of keratectasia after corneal refractive surgery. 4. Age 40 year-old or more.

Exclusion criteria

Exclusion criteria: Those who reveal one or more of following factors; 1. Thinnest corneal thickness is less than 400 um. 2. Corneal stromal opacity 3. Those who implanted artificial cardiac pacemaker or similar devices. 4. Ocular diseases, such as scar, herpetic infection, or nystagmus. 5. Infectious corneal disorders with unkonwn causes. 6. General diseases that can affect the corneal wound healing 7. Nallow angle, pregnancy, breast feeding 8. Occupation that is not allowed performing corneal refractive surgeries 9. Age less than 14 year-old

Design outcomes

Primary

MeasureTime frame
Change of visual acuity, manifest refraction, keratometric value, and corneal topography

Secondary

MeasureTime frame
Decrease of best corrected visual acuity, decrease of endothelial cell counts, and frequency of complications

Countries

Japan

Contacts

Public ContactJun Shimazaki

Ichikawa General Hospital, Tokyo Dental College Department of Ophthalmology

jun@eyebank.or.jp047-322-0151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026