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Clinical studies on the safety and efficacy of platelet rich plasma used in anterior cruciate ligament reconstruction

Clinical studies on the safety and efficacy of platelet rich plasma used in anterior cruciate ligament reconstruction - Clinical studies on the safety and efficacy of platelet rich plasma used in anterior cruciate ligament reconstruction

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000014694
Enrollment
5
Registered
2014-08-01
Start date
2014-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rupture of anterior cruciate ligament

Interventions

Use of PRP to the ACL reconstruction patients

Sponsors

University of tsukuba Department of Orthopaedic Surgery
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients operated ACL reconstruction in our hospital

Exclusion criteria

Exclusion criteria: History of infection(septic arthritis of the knee, femur / tibia osteomyelitis) / compromised host (Child-Pugh score A-C, diabetes, immunodeficiency, chronic renal failure, cirrhosis of the liver) - autoimmune disease(Various collagen diseases such as rheumatoid arthritis, systemic lupus erythematosus) Anemia (hemoglobin 10 g / dl or less) Blood disease(Coagulation and fibrinolysis abnormalities such as hemophilia) Anticoagulant used (such as aspirin, warfarin) Patients with a suspected history of malignancy within 5 years prior to the date of consent Patients who study physician determines that it is not suitable as a target

Design outcomes

Primary

MeasureTime frame
The presence or absence of adverse events in the follow-up period and at the time of surgery 1.Change in the vital signs when it is inserted into the intra-articular ligament with PRP 2.Joint fluid culture of postoperative drain effluent 3.Swelling of knee joint during follow-up times 4.Infection sign during 2weeks

Countries

Japan

Contacts

Public ContactYU TANIGUCHI

Univercity of Tsukuba Orthopaedic surgery

cindy.forever911@tsukuba-seikei.jp029-853-3219

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026