cancer and sarcoma
Conditions
Interventions
Administering metformin.
Sponsors
Okayama University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects who received a full explanation of the study and gave a written informed consent. 2. Subjects who can complain abnormal and subjective symptoms if they suffer from them during the study.
Exclusion criteria
Exclusion criteria: 1. Subjects who have received insulin therapy for diabetes mellitus. 2. Subjects who have the previous medical history of lactic acidosis. 3. Subjects who have received hemodialysis. 4. Subjects who have serious hepatic dysfunction. 5. Subjects who have the previous medical history of shock status, heart failure, cardiac infarction, pulmonary infarction and hypoxia. 6. Subjects who have drinking habit. 7. Subjects who are dehydration, 8. Subjects who have the previous medical history of severe ketosis, diabetic coma and type 1 diabetes. . 9. Subjects who have severe infection and serious trauma. 10. Subjects who are malnutrition, starvation, adrenal insufficiency and pituitary gland dysfunction. 11. Pregnant wouman 12. Subjects who are allergic to medicines. 13. Subjects who have been enrolled in the other clinical trials within last 4 months before the administration of metformin and administered any investigational new drugs. 14. Other subjects who are judged to be ineligible in this trial by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ability to produce cytokines (IL-2, TNF alpha, IFN gamma) and differentiation (memory, regulatory etc.) in peripheral blood T cells. | — |
Countries
Japan
Contacts
Public ContactMototsugu Watanabe
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of General Thoracic Surgery and Breast and Endocrinological Surgery
Outcome results
None listed