autosomal dominant polycystic kidney disease(ADPKD)
Conditions
Interventions
None listed
Sponsors
university of tsukuba,faculty of medicine,department of nephrology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ADPKD
Exclusion criteria
Exclusion criteria: The patient who study responsibility doctor or study allotment doctor judged inappropriate patient. The patient who was not agreed informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the increase of kidney volume | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Aggravation speed of renal function (eGFR or the inulin clearance (2) Death (the cause of death:) Infectious disease, malignant tumor, cardiovascular disease, cerebropathy, liver failure, respiratory failure, sudden death, other (accident, fall) ignorance) (3) Kidney composition endpoint (more than 25% drop of dialysis introduction, renal transplantation, 1/sCr or eGFR, renal artery embolus therapy) (4) Cardiovascular event (cerebral hemorrhage, subarachnoid hemorrhage, cerebral infarction, myocardial infarction, angina, heart failure, peripheral artery stenosis to need hospitalization) (5) Infectious disease (cyst infection, large intestine diverticulitis) to need hospitalization (6) Cyst bleeding to need hospitalization (7) Serious liver damage (an ascent more than the twice the standard value upper limit of total bilirubin and a rise more than 3 times of the standard value upper limit in serum ALT or AST) (8) Kidney plasma flow quantity (9) Prevalence (10) Gene variation | — |
Countries
Japan
Contacts
Public ContactHirayasu Kai
university of tsukuba,faculty of medicine department of nephrology
Outcome results
None listed