Efficiency of hydroxyethyl starch on circulatory dynamics in major abdominal surgery of hepatobiliary or pancreas system compared with using vasoconstrictive agents

Efficiency of hydroxyethyl starch on circulatory dynamics in major abdominal surgery of hepatobiliary or pancreas system compared with using vasoconstrictive agents - Efficiency of hydroxyethyl starch on circulatory dynamics in major upper abdominal surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014667

Enrollment

100

Registered

2014-07-31

Start date

2014-07-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

surgical patients scheduled for hepatobiliary or pancreas systems

Interventions

Two anesthetic managements are planned in cancer resection surgery of hepatobiliary or pancreas system. One is that circulation is maintained with the use of vasoconstrictive drugs (control). The othe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for cancer resection of hepatobiliary or pancreas system

Exclusion criteria

Exclusion criteria: Patients with severe esophageal varices, esophageal ulcer or cancer, and problem of opening mouth. Patients receiving esophageal cancer surgery. Patients in whom operation method is changed during operation.

Design outcomes

Primary

Measure	Time frame
Oxidative stress is evaluated by measuring 8-OHdG in blood or urine before the start of surgery and the end of surgery. Intraoperative circulatory system is evaluated by esophageal echocardiography.	—

Countries

Japan

Contacts

Public ContactMasahiko Tsuchiya

Osaka City University Medical School Department of Anesthesiology

oxymasa@ea.mbn.or.jp06-6645-2186

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026