Healthy volunteer
Conditions
Interventions
SAMe yeast: 0mg/day Duration: 12weeks
SAMe yeast: 500mg/day Duration: 12weeks
SAMe yeast: 2500mg/day Duration: 12weeks
Sponsors
CPCC Company Limited
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Males and females aged 50 to 74 years old (2)Subjects who feel discomfort and/or pain on knee joint within the last 6 month, and the discomfort and/or pain are still continuing
Exclusion criteria
Exclusion criteria: (1)Patients being treated for rheumatoid arthritis (2)Subjects who have a weak stomach, be suspected of gastrointestinal disease and/or have diarrhea routinely (3)Subjects who have previous medical history and/or current medical history of serious diseases (e.g., heart, liver, kidney, pancreas, and/or digestive organ) (4)Subjects who have hypertension (not less than level 3) (5)Subjects who continuously use anti-inflammatory agent or muscle relaxant (6)Subjects who continuously use pack and/or topical cream etc. on knee and/or leg region (7)Subjects who continuously use medicines and/or Chinese herbal medicine, and can't stop using during this trial (8)Subjects who use functional foods that have mitigation or treatment effect for joint pain (e.g., amino acid, protein, vitamin D, chondroitin, collagen, and/or glucosamine), and can't stop using during this trial (9)Subjects who have previous medical history of drug and/or food allergy (10)Subjects with excessive alcohol-drinking behaviors (11)Subjects who contract or are under treatment for psychiatric disorder (12)Subjects who have been enrolled in the other clinical trials within about last 1 month (13)Subjects who are judged as unsuitable for the trial by the investigator or subinvestigator for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Questionnaires(JKOM) | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical examinations Blood test Urine test Questionnaires(VAS, bodily sensation) | — |
Countries
Japan
Contacts
Public ContactMakoto ICHINOHE
CPCC Company Limited Plan sales department
Outcome results
None listed